Posted by linkadge on December 12, 2004, at 14:30:29
In reply to Re: Reserpine + TCA in the treatment of depression, posted by Racer on December 12, 2004, at 11:14:22
Yeah, reserpine actually causes ser/nor/dop to leak out of the synaptic terminals. The neurotransmitter is quicky metabolized as it is not really fired, but rather leaded out.
In the presence of a TCA, the neurotransmitter doesn't get recycled but rather reputake is blocked and it has more chance of reaching is destination.
Imobility time was decreased even over that of TCA alone.
Linkadge
poster:linkadge
thread:428196
URL: http://www.dr-bob.org/babble/20041211/msgs/428334.html