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Re: Zoloft vs. Wellbutrin as dopaminergics » jujube

Posted by KaraS on November 28, 2004, at 0:06:31

In reply to Re: Zoloft vs. Wellbutrin as dopaminergics » KaraS, posted by jujube on November 27, 2004, at 19:33:30

> See table 3.8 on SSRIs compared to Clomipramine and the "Effect of Uptake of their metabolites in vitro" found at:
>
> http://www.preskorn.com/books/ssri_s3.html#tab3-8
>
> Obviously, since Wellbutrin is not a SSRI, it is not on the chart.
>
> If you have already seen this, sorry for the duplication.
>
> Tamara
>
> > Perhaps there is a synergistic effect with Wellbutrin because of the NE/DA combination whereas Zoloft's serotonergic activity might counterbalance or offset it's dopaminergic activity. Might the end result be more of a dopaminergic effect with Wellbutrin?
> >
> > I am suggesting this because I believe that I need dopaminergic assistance and I took Zoloft but I was able to discern only a serotonergic effect from it. I felt no motivation, was extremely apathetic and had no sex drive. I realize that others might have a different response to Zoloft but I'm still left wondering about it's net dopaminergic effects.
> >


Thanks. I hadn't seen that. Too bad, as you say, that they didn't include other medications in the chart. It would be interesting to compare them.


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