Posted by pseudonym on November 22, 2004, at 14:18:16
In reply to I have got Lyrica today!!, posted by Kristel on November 22, 2004, at 11:42:57
First off, is the doctor prescribing this off-label because you showed him the clinical trial evidence, or was he/she aware of pregabalin's clincal trial efficacy beforehand?
The clinical trial's I have read show no efficacy for social anxiety below 300mg, and waiting three days to acclimate yourself is not long in the scheme of things. For comparison, Americans may have to wait years before Pfizer gets approval. Who knows?
Pregabalin's half-life is rather short, 6.3 hours, which is why twice a day or three times a day is the regimen chosen in the trials.
According to clinical trial evidence, the day you're most likely to experience an adverse event is day 6, so even if you feel dizzy and tired 6 days from now, I wouldn't say it has necessarily failed you at that point.
poster:pseudonym
thread:418966
URL: http://www.dr-bob.org/babble/20041118/msgs/419013.html