Posted by jerrympls on November 21, 2004, at 16:34:41
In reply to Re: Can Risperidal or Zyprexa be used for insomnia, posted by B2Chica on November 21, 2004, at 15:23:10
> Jerry!
> boy do i relate. my pdoc is getting frustrated with this iinsomnia of mine. with you..i've tried: sonata, ambien, trazodone, benzo's, seroquel. took zyprexa a year ago and that did make me tired but... on risperdal now, first two nights it conked me out, but not now (two weeks on). luckily i think my depression is setting in and i'm starting to wind down before midnight now...
> i guess i'm not much help, but i'm right there with you...wide awake and mind racing. h@ll, anymore, even when i'm depressive my mind won't shut down easily.
>
> sorry i have no good suggestions...
> btw, what is halcion and chloral hydrate? is one of them haldol...my pdoc mentioned that to me but i got scarred, so we went with risperdal.
> b2c.
>
>
> > I'm having a horrific time with insomnia. I've tried ambien, sonata, chloral hydrate, trazodone, seroquel, benzos, restoril, halcion and either they didn't work or worked for a while and then pooped out.
> >
> > I'm on Ambien 20mg and Trazodone 100mg now and the Trazodone make me feel HORRIBLE and gives me terrible, terrible nightmares.
> >
> > So what about Risperidal or Zyprexa? Are they used? I've read that the addition to an antidepressant, Risperidal can be helpful for treatment resistant depression. But is it sedating?
> >
> > Any help here would be GREATLY appreciated!
> >
> > Thanks
> > Jerry
>
>Halcion is a benzo sleep aid like Restoril. Chloral Hydrate is in a class of it's own. It's been around for a LONG time but was put on the back shelf as new sleep aids emerged. Here's some info I got from rxlist.com:
The mechanism of action by which the Central Nervous System (CNS) is affected is not known. Chloral hydrate is readily absorbed from the gastrointestinal tract following oral administration; however, significant amounts of chloral hydrate have not been detected in the blood after oral administration. It is generally believed that the central depressant effects are due to the principal pharmacologically active metabolite trichloroethanol, which has a plasma half- life of 8 to 10 hours. A portion of the drug is oxidized to trichloroacetic acid (TCA) in the liver and kidneys; TCA is excreted in the urine and bile along with trichloroethanol in free or conjugated form.
Hypnotic dosage produces mild cerebral depression and quiet, deep sleep with little or no ''hangover''; blood pressure and respiration are depressed only slightly more than in normal sleep and reflexes are not significantly depressed, so the patient can be awakened and completely aroused. Chloral hydrate's effect on rapid eye movement (REM) sleep is uncertain. Chloral hydrate has been detected in cerebrospinal fluid and human milk, and it crosses the placental barrier.
poster:jerrympls
thread:418487
URL: http://www.dr-bob.org/babble/20041118/msgs/418712.html