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Re: Ketamine Experiences /Ketamine and MAOIs » cubbybear

Posted by SLS on November 18, 2004, at 9:05:22

In reply to Ketamine Experiences /Ketamine and MAOIs, posted by cubbybear on November 17, 2004, at 22:54:29

Hi.

I don't think you will find much definitive information regarding the combination of an MAOI and ketamine. I found only one citation on Medline describing the combination, and it reported no adverse interaction between the two drugs.

I also found the following:

Intravenous induction agents

"All the commonly used intravenous induction agents (thiopentone, propofol, etomidate and ketamine) have been used uneventfully in patients taking MAOIs.14,16 The classical MAOIs can cause a decrease in the hepatic metabolism of barbiturates which requires a reduction in dose.17"

http://www.rcoa.ac.uk/docs/b21_monoamine.pdf

Theoretically, a sympathomimetic drug like ketamine should not be combined with an MAOI, but it is well recognized that Ritalin, Dexedrine, and noradrenergic TCAs are safe to use.

What are you to use ketamine for?


- Scott

 

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