Posted by King Vultan on November 16, 2004, at 16:12:29
In reply to Re: SCARED Pdoc wants to raise meds again, posted by tampagirl70 on November 16, 2004, at 12:41:10
> OCD is my biggest issue. The depression comes along for the ride when I start obsessing. I was on Effexor for a while a long time ago and I don't think it helped. I was also taking Norpramin and it gave me terrible dry mouth and made me sweat a lot. ARen't most SSRIs are good for OCD if taken in higher doses?
SSRIs are indicated for OCD, and I did find Zoloft helpful for mine, but I felt Effexor was just about as effective. I never took more than 150 mg/day of Effexor, though, and mostly less than that because it gave me such bad insomnia. The Norpramin (desipramine) problems do indicate that other drugs that significantly affect norepinephrine reuptake may tend to cause the same kinds of side effects in your particular case.One thing I've heard of being used for refractory OCD is adding a low dose of an atypical antipsychotic, such as Risperdal or maybe Zyprexa. Some of these drugs are relatively selective for blockading the serotonin-2A receptor at low dosages, and this can be helpful in augmenting SSRIs in treating OCD. The problem that can happen sometimes just trying to deal with the problem using high doses of an SSRI is that they can result in this receptor becoming overly stimulated, which can actually make OCD worse, as well as cause other side effects.
Todd
poster:King Vultan
thread:416633
URL: http://www.dr-bob.org/babble/20041113/msgs/416771.html