Posted by KaraS on November 12, 2004, at 15:27:22
In reply to Re: SSRIs and amotivation, posted by j. Backer on November 12, 2004, at 13:59:23
> im on effexor 300mg and dexadrine 20mg time-release.
> i slept like 16 hours the other day im always exausted, i just dont get it. iv always been like this, i failed school because i was always sleepin (even on adderal). i can fall asleep after a tripple esspresso EASY. i struggle staying awake at work, behind the wheel ect...
>
> i defently could use suggestions, any.
> peace jDo you EVER feel any stimulation from stimulants?
If not, you might have what I have: hypersensitive presynaptic dopamine autoreceptors. In this condition the autoreceptors are overly vigilant in keeping low levels of dopamine in your synapses. When more dopamine is introduced, instead of stimulation, your autoreceptors reduce their output and the net effect is that you feel tired. I have recently found this out about myself and am exploring ways to deal with it.Serotonergics (including Effexor) also have a dampening effect on dopamine.
K
poster:KaraS
thread:414533
URL: http://www.dr-bob.org/babble/20041108/msgs/415106.html