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Re: Bipolar Illness And Psychostimulants :- o !!!!

Posted by linkadge on November 7, 2004, at 11:10:18

In reply to Re: Bipolar Illness And Psychostimulants :- o !!!!, posted by Chairman_MAO on November 7, 2004, at 3:06:45

In other words yes it can.

Mania is proposed to be associated with hypocholinergic function. This is why TCA
are often the worst for initiating a
manic episode.

However stimulants strongly activate the prefrontal cortex, and often strongly potentiate the cholinergic systems. This can lead to mood depression and/or stabalization via prefronal cortex activation.


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URL: http://www.dr-bob.org/babble/20041103/msgs/412868.html