Posted by jboud24 on November 2, 2004, at 18:10:25
In reply to Somebody think this through for me..., posted by lostforwards on November 2, 2004, at 14:52:56
Gosh this is complex. I think whoever put you on 2 antipsychotics probably made a mistake in doing so. I mean their intentions were probably good, its just that unless your dopamine levels are extremely elevated, ala psychosis/schizophrenia, anti-psychotics, particularly that anti-psychotic you were taking that was a typical (the other one, not the risperdal) probably lowered the dopamine levels to too low a level. I mean, even very low dose Risperdal antagonizes DA2/3 receptors to a high degree, so adding a phenothiazine that targets only the D2/D3 receptors probably lowered the DA levels too much.
You're going to have to respond back and tell me the current dose of the Risperdal (I still remember the old dose of 1,2,and 3mg) and the name (chemical if possible) of the phenothiazine you took and at what dosages and for how long you took the phenothiazine. Also, what country do you live in?
I think you should look into a drug that will assisst you in overcoming the AP-induced side-effects that could modulate or restore some of the DA function back to a better level. I don't remember what your diagnosis is exactly, but Abilify at low doses may help alleviate the side-effects you are experiencing by exerting a stabilizing function on your DA system. I also strongly believe that a drug call Mirapex (pramipexole) would alleviate all if not most of the AP-induced side-effects. In case you dont know what Mirapex is, it is a dopamine agonist used to treat Parkinson's and Restless Leg Syndrome, as well as off-label uses for depression and anxiety. I really think that Mirapex could help you.
Lostforwards, I know what you are going through is rough, and my prayers are with you. If you need anything else, don't hesitate to ask!
Best Wishes
Justin
poster:jboud24
thread:410690
URL: http://www.dr-bob.org/babble/20041029/msgs/410772.html