Posted by OldPunk on November 1, 2004, at 18:48:19
In reply to Re: HELP -Celexa/Wellbutrin/Augmentin/Dextromethorphan, posted by tampagirl70 on November 1, 2004, at 15:32:33
> At this point, I don't even need the cough syrup and I stopped taking the DXM.
Probably a very good idea. According to the C450 substrates/inhibitions chart at http://medicine.iupui.edu/flockhart/table.htm
(Thanks to Chairman MAO's post on April 1, 2004), the DXM is metabolized using the 2D6 isoform, which is inhibited by Wellbutrin/bupropion. The Wellbutrin is itself a substrate for 2B6. Celexa also inhibits 2D6 and is a substrate for 2C19.The best I can guess is that it's just going to take a long time for the DXM to work its way out. For *ME* it extends the time to clear out the cough syrup's bleh-ness by a factor of 6, without really extending its beneficial effects. However, the DXM should eventually work its way out.
poster:OldPunk
thread:409980
URL: http://www.dr-bob.org/babble/20041029/msgs/410317.html