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Moclobemide again

Posted by sabre on October 13, 2004, at 1:37:04

After using Moclobemide for a week - 150mg in one morning dose, I increased to 2 doses/day for a total of 300mg for a couple of days. Felt awful...depressed, stuffed and antisocial. Couldn't get off the couch or out from under the doona.

Cut the dose back to 75mg x twice a day. Interestingly, this was more energising than the single 150mg dose/day. I even experienced some insomnia whereas I hadn't felt it at 150 or 300...quite the opposite in fact.

The side effects of palpitations and burping were annoying. I read on some cardiac sites that some people experience irritation of the vagal nerve through acid reflux or gas pressure that can cause the palpitations. My heart rate wasn't elevated. Just seemed to miss a beat and flop approx every 10 beats.
In addition when I tried to race (running) the vasodilation effect seemed to create a lag effect in the first couple of kms. Beyond that it was okay.
I found the low dose made me more happy but I started experiencing more panic at the same time. Strange. I felt like my body was revving...sweaty armpits and increased git effects.

Decided to go off it a couple of days ago because I just didn't feel like it was going to help the social anxiety. The studies I have looked at that helped SA used high doses ie at least 450mg. I think I'd be comatose on this.

This therapeutic dose business just doesn't make sense to me. How can everyone have the same td?
Body weight;lean muscle mass; sex; age; metabolism; psyche conditions all vary from person to person. I have found now that I get a strong effect from 25% of the recommended therapeutic dose.

Not sure what to do now. I found an online book written by a pyschiatrist who 'cured' her own depression by trying supplements of vit c, vit B, tryptophan and tyrosine. I've started on the
vitamins and have got some tryptophan to use.

Has anyone tried this program?
http://www.thewayup.com/ebook/f/TheWayUp.pdf

Over the last few days I've been relying on the Propranolol and feel depressed but then again I've probably been mucking around too much with the Moclo experimentation.
I just feel like the serotonin and noradrenaline might not be the answer for SA, for me anyway.

sabre


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poster:sabre thread:402483
URL: http://www.dr-bob.org/babble/20041012/msgs/402483.html