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Re: Beyond Parnate

Posted by Nohope on October 5, 2004, at 5:53:08

In reply to Re: Beyond Parnate, posted by linkadge on October 4, 2004, at 8:41:00

Hi Linkadge.

Your response to Parnate is interesting. Maybe you could briefly describe your Parnate trial?

The reason I say this is that, in 14 yrs of trying medication after medication, I have never come across one like Parnate, where you must wait so long for a sustained response - I suspect that many people may have given up on it too soon.

When I first started at 30mg/day, there was an immediate, enormous improvement in anxiety levels. After about a week, this began to fade. After about 2 weeks, an antidepressant response kicked in that could only be described as a calm euphoria (simply wonderful). After a couple of weeks, this faded and I almost felt unmedicated. I was suspecting the worst, and investigating Nardil as a potential alternative. I then upped the dose (now at 60mg/day): exactly the same response repeated itself. However, after 2-4 weeks of the 'unmedicated' state, a strong, sustained antianxiety and antidepressant effect kicked in (and has remained).

I guess what I am trying to say is that people's response to Parnate can be complex, and it can take many weeks (for me about 10) before sustained, positive results are realized (for other medications, by about week 4 I was pretty much as good as I was going to get.) So, I am wondering if you gave Parnate an adequate trial. If not - maybe it is still an option for you?

Best of luck

Nohope

> Parnate worsened my depression, but other AD's made it better. It really depends on the person.
>
> The combinations and permutations are infinite.
>
>
> Linkadge
>


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poster:Nohope thread:398633
URL: http://www.dr-bob.org/babble/20041002/msgs/399055.html