Posted by Racer on October 4, 2004, at 11:56:08
In reply to Re: I've looked it up now... » Racer, posted by karaS on October 4, 2004, at 0:31:27
Sorry, I looked up Effexor at the same time, but didn't think to include the information: the regular Effexor also reaches steady state after three days, but only with split doses. I think the half life of Effexor is not a lot shorter than Cymbalta, but I guess the metabolites are shorter lived, too, which would require the multiple doses throughout the day. That's something for someone who actually knows something to tell you.
Did the Effexor work for you? If so, get excited about Cymbalta. For me, it's been very similar, but with all the rough edges smoothed out in a very big way. That 'brain zap' feeling? With Cymbalta, it only lasted a few days, and it wasn't the same zappy feeling, just a sort of -- sensation -- in the same areas; much more a sense of wooliness than actual static like zaps. The sweats from Effexor? A few days of them with Cymbalta, now back to normal for me. That's been the case with most of the adjustment phase effects of Cymbalta for me: a few days of discomfort, then they've gone away.
I'm sorry to say that it's not doing much of anything for my depression, though. Neither did Effexor. It is improving my physical discomfort, though -- I have arthritis (common in people who've ridden for years), and sometimes the pain can keep me awake at night. Not with Cymbalta, though -- I'm sleeping just fine, and my joints feel better than they have for years. Still some pain, but well within tolerable limits. It's a nice drug, and I wish it was showing some signs of working for me.
I waited to take my first dose, too. When I did take it, about three hours later I started to feel so calm, and so relaxed, just floating. That lasted the first few days, then I went back to normal. Enjoy that initial cloud float, and good luck with it.
poster:Racer
thread:398577
URL: http://www.dr-bob.org/babble/20041002/msgs/398799.html