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Re: Difference, methylphenidate d-and l-amphetamine?

Posted by geno on October 1, 2004, at 1:45:44

In reply to Re: Difference, methylphenidate d-and l-amphetamine?, posted by utopizen on September 30, 2004, at 11:29:10

Guys, I dont know if i posted, but i do have Klonopin from my doctor. He told me to basically take it as needed in the day, but take it at night to sleep.
This doctor is very good. Actually he not even a p-doc, but he is very helpful and not anti-drug, which if i never have gotten Adderall or klonopin, and suboxone , I would be still using or back in rehab. ALong with my ADD, and symtoms.
Most "addiction Specialist" think if you abuse a drug or alcohol, you will abuse everything. I dont agree 1 bit. I dont care if a neuropsychopharmotherapist whatever that is, tells me different. Im very specific with what i take, how much i take, even during my opiate use, i always was afraid to take alot at once. I always took more throughout the day.
But some drugs like alcohol can make one prone to say go back to opiates or coke. But i use this example. My bottle of klonopin still has pills in it by my next appointment, and the only reason i do take more adderall, is because i cannot or my insurance wont pay for adderall xr, so i dont get a full days worth of positive results.
If I wake at noon, take my first adderall, by 5, i have to take the second dose, or by 6pm, i will defenitely feel the comedown. So this works out good, but by 10pm, i need another dose. Ok well 2x a day, i dont have another dose unless i take one , so im not taking it to abuse it. Also, im up to 4am, so its not like betime is 11, or even so, i would wake up at 8pm, and then by 5, i would be again without a dose.
So dexedrine spanuals last 10hrs, and insurance pays for it. So if and im sure my doc will work with me, add something or switch me to dex spanuals, or even a 1 dose of spanuals and 1 dose of regual dex. Lowering my adderall dose below 30 wont work, say 20mg 3x daily, because 30mg is not enough some days. But from being very tolerant,, i sure if they had a 40mg pill, i would would handle it. Iv tried 45, just once and had no anxiety. But that was just to see if higher doses make a difference, and i really didnt.
Now iv read studies of doctors perscribing children or young teens combos, of adderall, and welbutrin or even adderall xr, and another dose of reg adderall. One study i remember the 14 yr old had severe add, and the doctor closly monoriting him, had him on Ritalin and Adderall, I belive adderall was 20mg XR and then evening Ritalin SR, or regualar , dose i belive was 10mg.
So, even welbutrin and adderall, may help alot, due to somewhat of a dopamine/Ne double up, but still Welbutrin or straterra do release dopamine, but not in the straitium or Nucleus accumbens.
Im sure most doctors know not to perscribe 2 drugs that are prone to have this profile, like Ritalin and amphetamine or dex and ritalin.
But , id like to start on dexedrine and see how i feel, and from most users, it works very well, most often better than the adderall. I also believe the D-isomer in adderall , which is 1/4 of the dose, is the primary isomer for mental stimulation and effect, and dopamine release from the Nuc ACC.

But here is a very interesting question. IF you take a natural dopamine precusor, say L-tyrosine, and due to the different sites of Dopamine, will this increase such so there is more DA availablein the reward pathways, such as the Nucleaus accumbens, when taking amphetamines? Im researching for a supplement which actually has these properties. I will post , i have a few already a possibility, but need more research.

geno


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