Posted by quarterwit on September 6, 2004, at 9:53:02
In reply to Re: Parnate to Cymbalta?, posted by SLS on September 5, 2004, at 9:33:46
Thanks Scott, and tracking your own Cymbalta progress, I'm sorry about the poor response. But despite the quick-response marketing hype, maybe a full trial of 4-6 weeks still makes sense? There have been so many times when I've wondered "would that 9th week at Effexor 225 mg (the highest I could handle) had made a difference?"; "would that 6th week at Wellbutrin 150-300 mg (highest I could take, but better SE profile than Effexor) had made a difference?"
These symptoms I think like total lack of motivation, feeling leaden and slow, resulting social and other problems are particularly tough to deal with. I have the same problems and feel as if I'm living a half-life. Tough to take and I'm fed up, as you must be.
With your Parnate expereince, did AD effects poop out or did you never have them to begin with?
Keep us posted --
> > Thanks for reply. I'm on 175 mg of Lamictal -- once beyond 100 it became sedating, with or without Parnate. I'm leaning towards staying on Parnate for full trial. Up to 50 on Tuesday, then onwards up.
>
> > BTW, why did you go off the Parnate?
>
> It didn't produce an adequate antidepressant response - even at 150mg. I tried mixing it with Lamictal, desipramine, thyroxine, Dexedrine, and bromocriptine.
>
> > Also, any suggestions on how to spread out dose once it gets to 60? How about 30 in morning, 30 early afternoon?
>
> Perfect.
>
> If low blood pressure becomes an issue, you can try spreading it more evenly, with the last dose to be given at 3:00pm. If insomnia does not develop, you can spread it over a longer period of time. I found that the low blood pressure became less pronounced over time.
>
>
> - Scott
poster:quarterwit
thread:386419
URL: http://www.dr-bob.org/babble/20040904/msgs/387028.html