NE alpha-2 antagonism + reuptake inhibitors = AD++

Posted by SLS on September 1, 2004, at 20:16:29

Here's a neat little piece I found:
Alpha2-adrenergic receptor blockade markedly potentiates duloxetine- and fluoxetine-induced increases in noradrenaline, dopamine, and serotonin levels in the frontal cortex of freely moving rats.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9375697

This provides a nice pharmacological rationale for the use of Remeron or Buspar (with its 1-PP metabolite) as augmentors.

- Scott

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NE alpha-2 antagonism + reuptake inhibitors = AD++ SLS 9/1/04
Re: NE alpha-2 antagonism + reuptake inhibitors = AD++ » SLS zeugma 9/1/04
Re: NE alpha-2 antagonism + reuptake inhibitors = AD++ » SLS King Vultan 9/1/04
Re: NE alpha-2 antagonism + reuptake inhibitors = AD++ » King Vultan SLS 9/2/04
Re: NE alpha-2 antagonism + reuptake --sls alesta 9/2/04
Re: NE alpha-2 antagonism + reuptake --sls linkadge 9/2/04
Re: NE alpha-2 antagonism + reuptake --sls SLS 9/2/04
Re: NE alpha-2 antagonism + reuptake inhibitors = AD++ Sad Panda 9/3/04
Re: NE alpha-2 antagonism + reuptake inhibitors = AD++ SLS 9/3/04
To SLS » SLS EERRIICC 9/15/04
Re: To SLS » EERRIICC SLS 9/16/04

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