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Re: Im depressed » ace

Posted by Sad Panda on August 23, 2004, at 21:44:18

In reply to Re: Im depressed » Sad Panda, posted by ace on August 23, 2004, at 18:55:03

> > > > Hi Ace,
> > > >
> > > > How about adding an NE booster like Nortriptyline? It's giving me a bit of a lift to my Effexor & is strangely lacking in side effects. It would be safe with Nardil, only problem I can see from this combo is possible hypotension.
> > > >
> > > > Cheers,
> > > > Panda.
> > > >
> > >
> > >
> > > I added Reboxetine (NE booster) before and within a couple of doses I was depressed.
> > >
> > > do you thing the same would happen with a TCA?
> > >
> > > Take Care friend,
> > >
> > > Ace.
> > >
> > >
> >
> > Hi Ace,
> >
> > I don't really know. It could explain why you had a bad reaction to clomipramine since it's metabolite is a potent NRI. OTOH, Nardil raises levels of NE too, so I guess you would have to try it to find out.
> >
> > Cheers,
> > Panda.
> >
> >
> >
>
> Panda, but the major point is I have given up on both drugs after 2/3 days!! Maybe the paradoxical depression would completely dissipate after a week and produce an AD/ Anxiolytic effect???
>
> What u think????
>
> Ace
>
>

Hi Ace,

I don't know the answer to that one, if you are going to add an NRI again then maybe you need to do it in hospital under supervision to see if the inital paradoxial reaction does go away.

Have you tried the other atypical AP's? Risperdal is a very potent 5-HT2A antagonist like Zyprexa is, it's the first receptor they both block, but has a lot less H1 & M1 activity. Abilify has to be worth a try too.

Cheers,
Panda.


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