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Re: Lamictal and Memory Loss

Posted by SLS on August 16, 2004, at 14:31:36

In reply to Lamictal and Memory Loss, posted by yellowhat on August 16, 2004, at 13:26:31

> I've been on 10mg Zyprexa and 200mg (twice daily) Lamictal for one year. My doctor recently took me off the Zyprexa at my request, but I'm still on the Lamictal. I recently heard that Lamictal causes severe short-term memory loss. The reason I got off of the Zyprexa was to try and regain the intelligence I'd obviously lost while on Zyprexa. I don't want to be stuck on yet another medication that effects my intelligence. Feedback?


I find that when my dosage of Lamictal exceeds 200mg, it significantly impairs my short term memory and blunts my cognitive capacity. I purposely lowered myself from 300mg to 150mg three weeks ago in an effort to minimize these effects. I don't seem to have lost the small antidepressant effect I glean from Lamictal, but I believe this is because the addition of memantine, a glutamate NMDA receptor antagonist, has helped offet the loss of glutamate release inhibition resulting from the reduction of Lamictal dosage.

Lamictal might have been more of a culprit than the Zyprexa. Very few people ever complain of cognitive impairment from Zyprexa.


- Scott

 

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