Posted by chess on August 16, 2004, at 3:46:44
In reply to Re: half lifes » andromeda, posted by Larry Hoover on August 15, 2004, at 13:27:21
I've gone through this with Klonopin ...
Klonopin has a half-life of 18-50 hours, so you would think it could be taken just once or twice a day, but some people need to take it three or four times a day because even though its half-life is long its "duration of action" averages to around eight hours. Duration of action is the actual clinical therapeutic effect of the medication. There's a good biochemical explanation for it but basically half-life doesn't always mean how long the med will work therapeutically.
poster:chess
thread:377551
URL: http://www.dr-bob.org/babble/20040811/msgs/378127.html