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Re: Lithium and inositol: neurophysiological effects

Posted by linkadge on July 24, 2004, at 12:33:00

In reply to Lithium and inositol: neurophysiological effects, posted by Questionmark on July 23, 2004, at 20:25:25

I think that lithium is certainly the more robust neuroprotectant and neurotrophic agent.

Inositol is not terribly neuroprotective. I think it works best for depression and OCD. Lithium works for *some* forms of depression but is not as good for panic, and does almost nothing for OCD.

I believe that inositol works to increases the sensitivity of the serotonin receptor sites while lithium increases the firing of the serotonin neurons.

It does seem like the information out there is somewhat contredictory, and I don't know for sure myself.

Some researchers suggest that inostiol supplementation during lithium treatement might reduce side effects without reducing the effect.
I have often wondered this myself. Is inostiol depleation really necessary for the theraputic effect of lithium ?? Perhaps only the antimanic aspect??

One thing I do know is that inositol is *not* good for psychotic features of mood disorders while lithium is. Inositol really helped my depression but I felt a little bit out of control. Not manic, but kind of posessed. Lithium didn't make me feel as happy as I was on inositol but not depressed and much saner.


Linkadge



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URL: http://www.dr-bob.org/babble/20040724/msgs/369955.html