Posted by cpallen79 on July 14, 2004, at 19:45:12
In reply to Lexapro/Paxil/Zoloft, posted by pablo1 on July 14, 2004, at 16:37:55
Pablo, I think it's great that you are doing your homework. Lexapro, theorhetically, is a "clean" med that really hits serotonin only (in theory)... Others such as Prozac and Zoloft may not be as selective (hence you hear that they may be more activating. Paxil tends to be sedating, as does Luvox. I tihnk a stimulant combo might be a good idea, initially you may feel really icky as you will experience sudden drops in dopamine during the peaks and valleys, but that should smooth out eventually. Perhaps something like adderall and Lexapro would work? Another idea would be to add a very low dose of wellbutrin in to an ssri. Alone, wellbutrin can definetely increase anxiety, but with an SSRI, it might be "just right"
> Any comparisons between Lexapro, Paxil & Zoloft?
>
> Lexapro & Zoloft seem to have some dopamine effects (especially ZOloft), Paxil acts on acetylcholine muscarinic receptor whatever that is (see below).
>
>
> http://www.bol.ucla.edu/~nwoolf/
> "Acetylcholine has been suggested to play a prominent role in the mediation of memory (Woolf et al., 2001) and conscious activity in brain (Woolf, 1997; Perry et al., TINS, 22:273, 1999; Woolf and Hameroff, 2001). Acetylcholine muscarinic receptors affecting the phosphorylation of MAP-2 has implications for quantum computing. Quantum computing in brain microtubules may be tuned by MAP-2 according to Penrose-Hameroff Orch OR (Penrose, 1994; Penrose and Hameroff, 1995). Quantum computing in microtubules, and classical computing involving electrophysiological events around the membrane, may work together (see figure below)."
>
> Obviously I don't know what I'm getting into here but neither do the psychiatrists so I might as well try to research what I know is important for me.
poster:cpallen79
thread:366145
URL: http://www.dr-bob.org/babble/20040714/msgs/366282.html