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Re: Maprotiline / Oxaprotiline, metabol. or diff. drug » rod

Posted by SLS on June 22, 2004, at 7:01:22

In reply to Maprotiline / Oxaprotiline, metabol. or diff. drug, posted by rod on June 22, 2004, at 5:58:47

> Does anybody know if Maprotiline gets metabolised into oxaprotiline, or are they 2 different drugs.
> I didnt find an answer to this on the internet. So any info is much appreciated.
>
> thanks
> Roland


Hi Roland.

I infer from these two Medline abstracts that the two drugs are both parent drugs of similar parallel metabolites. They don't seem to be metabolites of each other. I think Chemist would be able to interpret the literature more definitevely.

What's up?


http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3984384

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=6464500


- Scott

 

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