Posted by psychosage on June 21, 2004, at 12:16:57
In reply to Re: Provigil affects norepinephrine, right? » zeugma, posted by King Vultan on June 20, 2004, at 14:51:56
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> > What sort of reaction did you have, and how did it help you have a vague comprehension of what it's doing?
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> > I took 100 mg Provigil this morning and promptly went back to sleep. I had some vivid dreams, more vivid than usual. This is the opposite of my experience with Strattera, where my dreams were completely suppressed by the drug's effect (NE reuptake inhibitors are specific inhibitors of REM sleep). But we already knew Provigil was not an NRI (that is why it is ineffective against cataplexy).
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> > For me so far, the only effect has been a calming one. Definitely not the noradrenergic rush I got from strattera, or from nortriptyline at low doses.
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> What I meant was all the research I did gave me a vague conception of how it works, not my reaction to it, which I don't understand and is apparently in the "rare" category. The stuff was intolerably sedating, and I was so sleepy I could barely function. Out of the 11 drugs I've tried, it was the only one with zero therapeutic effects. I could have perhaps used it as a sleep aid, but seeing as though the stuff is supposed to be a stimulant and is used for people with narcolepsy or by Parkinson's patients falling asleep in the middle of the day from their dopamine agonists, that really made no sense to me.
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> Todd
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>according to similar reactions to strattera, provigil might be sedating you because you might not have enough of the neurotransmitter{s} it is working on.
check the 3rd paragraph in "how to take strattera"
poster:psychosage
thread:358279
URL: http://www.dr-bob.org/babble/20040621/msgs/358615.html