Posted by zeugma on June 16, 2004, at 20:07:21
In reply to Re: Mechanism for Strattera CAUSING depression?, posted by TJO on June 16, 2004, at 16:47:03
One of the few clues we had was that NE reuptake inhibitors were THERAPEUTIC for melancholic depression, so it's ironic that while non-selective NE reuptake inhibitors (TCA's) have real efficacy for this disorder, selective ones like reboxetine and Strattera can worsen or induce such symptoms. Not only is it a black box, it's a black box whose output hardly seems to be amenable to conjecture yet.
I doubt scientists are going to make any real progress with psychotropics except by accident. I mean that for the foreseeable future (the next hundred years or so).
poster:zeugma
thread:353502
URL: http://www.dr-bob.org/babble/20040614/msgs/357379.html