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Re: OK, try a cholinesterase inhibitor + AD » Chairman_MAO

Posted by chemist on June 13, 2004, at 22:05:42

In reply to Re: OK, try a cholinesterase inhibitor + AD » SLS, posted by Chairman_MAO on June 8, 2004, at 9:22:42

hello, chemist here. a little problem with galantamine: it is not a cholinesterase inhibitor, rather acetylcholinesterase. as you should be aware, there is quite a difference. you will excarebate transmission at neuromuscular junction ACh, enhancing smooth-muscle function. you ought to try a true nootropic. all the best, chemist p.s. or at least a real cholinesterase inhibitor, not an ACh-I.


> Yeah, I should've mentioned that instead of simply hinting that it should be combined with an AD. I surmise that for BP1 folks who spend a lot of time at the manic end of the spectrum, cholinesterase inhibitors could be especially useful.
>
> I found that while on lexapro and Strattera, I could use galantamine (Reminyl, Nivalin) in moderate doses without exacerbating my depression. Fine titration is a requirement, however. If I took just a little too much, I fell into an an agitated, thought-frenzied, depressive state.


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