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Re: Respons to you question Chemist? » BRC

Posted by chemist on June 12, 2004, at 17:38:23

In reply to Re: Respons to you question Chemist?, posted by BRC on June 12, 2004, at 8:52:05

> Hi, Chemist thanks for your response. I did try Luvox years ago when this first began but I did not stay on it very long because I was forced to change pdocs and he changed my medication.
>
> I thought that most SSRI's acted in the same way by targeting serotonin. How does Luvox being a SSRI differ if it to targets serotonin like the Lexapro I am currently taking?

hi there...the best i could come upwith was that luvox is a very potent inhibitor of certain enzymes (CYP450) and that (R,S)-citalopram - you are taking (S)-citalopram, so i am not sure if this is true for (S)-citalopram - is not, and that apparently luvox ingestion raises melatonin levels, while (R,S)-citalopram (Celexa) does not. keep in mind that other liver enzymes are involved with melatonin, and that there is a balance between melatonin and serotonin that is indicated for mood. perhaps this is the difference, in that luvox modulates serotonin by both reuptake inhibition and the production of melatonin and/or inhibition of reuptake. sorry, i just don't know. anyone else? all the best, chemist


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