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Re: Maprotiline or Doxepine? Maprotiline for Burnout? » rod

Posted by Sad Panda on June 9, 2004, at 3:47:25

In reply to Maprotiline or Doxepine? Maprotiline for Burnout?, posted by rod on June 8, 2004, at 16:12:15

> Well, I actually started Doxepine (Sinequan) at only 25mg a few days ago. I am not sure if this is the right drug for me, because its really sedating and prolongs my sleep time, which is already too long. And also not really makes a social life at night possible, because of its unpleasant sedation.
> But it seems to reduce cortisol secretion, because I look less ugly in the morning, if I interpretate this right.
> Anyway, there is also Maprotiline, which I could often read in context with burnout or "exhaustion depression" (sorry, if the spelling is wrong).
> Can anyone compare this two drugs. Is Maprotiline energizing, disstressing? The right thing if one permanently feels exhausted for no reason?
>
>
> Other drugs I take are
> Nortriptyline 150mg
> Lamictal 50mg (dropping this)
> Neurontin 1500mg
> Abilify 7,5mg (I am not sure about this drug)
> Amisulpride 50mg
> Diphenhydramine 100mg
> Clonazepam 0,5mg
>
> thanks for reading
> Roland


Hi Roland,

Maprotiline & Doxepin are nearly gone & forgotten because the remaining TCA's do everything they can but better. Doxepin comes with the same side effects as Amitriptyline but it isn't an SRI which renders it rather useless except for sleep.

I would be inclined to use Amitriptyline at a dosage you can live with and adjust your Nortriptyline level accordingly using blood tests. You could drop Diphenhydramine too, it is rather weak compared to Amitriptyline & especially Doxepin. Also, it takes me about a month to develop tolerance to histamine blockade & then my sleep becomes very normal, YMMW.

As for your AED's & AP's, I think you might feel better after you get rid of one or two of them. It's an impressively long list, what is your DX? :)

Cheers,
Panda.


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