TRD Treatment Resistance Definitions

Posted by SLS on May 14, 2004, at 9:19:19

Simple system for staging antidepressant resistance

Stage Definition

I - Failure of at least one adequate trial of one major antidepressant class
II - Stage I resistance plus failure of an adequate trial of an antidepressant in a distinctly different class from that used in Stage I
III - Stage II resistance plus failure of an adequate trial of a tricyclic antidepressant
IV - Stage III resistance plus failure of an adequate trial of a monoamine oxidase inhibitor
V - Stage IV resistance plus failure of a course of bilateral electroconvulsive therapy

Source: Thase ME, Rush AJ. When at first you don’t succeed: sequential strategies for antidepressant nonresponders. J Clin Psychiatry 1997;58(suppl 13):24.

Thread

TRD Treatment Resistance Definitions SLS 5/14/04
Stage V - Woohoo! (nm) SLS 5/14/04
Re: Stage V - Woohoo! snapper 5/14/04
Re: Stage V - Woohoo! » snapper SLS 5/14/04
Re: Stage V - Woohoo! snapper 5/14/04

Post a new follow-up

Notify the administrators

Start a new thread

poster:SLS thread:346743
URL: http://www.dr-bob.org/babble/20040510/msgs/346743.html