Posted by jodeye on May 10, 2004, at 15:48:57
In reply to Re: Does Sonata/Amb.act on the same GABA as Klonopin?, posted by florence on May 10, 2004, at 14:06:02
> > I had succes with provigil for over 2 years; most of the time 50-100 mgs was enough. Now, I have tried up to 250 with not much improvement.
I have heard testimonials that NMDA antagonists can prevent stimulant tolerance. I can only wonder if they might prevent Provigil tolerance as well?
> > What is zopicom (sp.?).
Zopiclone (imovane(tm)) is what I call one of the Z-drugs... Ambien, Sonata, Imovane -- they all start with the letter Z. I think zopiclone has a longer effect than either Ambien or Sonata. It is a french molecule that can be obtained from Canada with a US doctors prescription. Under $20 a month. You should be able to find a monograph on a canadian web site. Since it is NOT an FDA approved drug, it can legally be imported because of the *compassionate use* legislation. FDA approved drugs are not legally importable yet.
> > The info about Klonopin came from an excellent website called Immune Support that has many different boards: Depression, Chronic Fatigue, Arthritis, Lupus. It has an article in their "Library" entitled Dr Paul Cheney discusses the benefits of Klonopin. It is an EXCELLENT site; well-monitored just like Psycho Babble.
Thanks. I'll check it out. I'm ready to ask my doc to prescribe Klonopin + Adderall (or Klonopin + Provigil) for my symptoms of fatigue and APD, and I have not yet seen the Klonopin dosing schedule you describe.
> > I am SO frustrated becuz I FINALLY find something that works (provigil plus sonata) and of course, since Sonata has such a short half life I had to take 3-4 pills a day to feel well. (not high or drunk: just normal!)
Sonata during the day? you say?
> > My pdoc is great but is afraid the DEA will come take her away id she keeps giving me scripts for Sonata.
After seven wonderful years together, my doc says that he is willing to prescribe virtually anything I ask for as long as there is the tiniest rationale for it. He has very little history prescribing stimulants though. Which makes me wonder what are a doctors legal issues in prescribing stimulants all of a sudden, and possibly at a somewhat higher dose than the PDR recommends. Is someone really watching him? How close?
> > She offered me Ambien last week but it didn't seem to work as well as the sonata; as far as lifting my mood. Plus, I had bad headaches from it. SO, that is why I am trying to research Klonopin. I hate to ask for yet another drug that may do little or nothing. I take Xanax but do not notice any antidepressant effects. In fact, I only need it to counteract the Provigil "meltdown".
What is the Provigil "meltdown?"
> > Any thoughts on how to find a drug that works on the same Gaba or part of the brain as Sonata?
Ambien, Sonata, and Imovane all work on the same GABA receptor subtype, but as to which part of the brain, hard to know.
--Jay
poster:jodeye
thread:345256
URL: http://www.dr-bob.org/babble/20040510/msgs/345464.html