Posted by SLS on May 7, 2004, at 9:13:45
In reply to Re: Which of the SSRI's are the most potent?, posted by linkadge on May 7, 2004, at 7:59:22
> Is that paxil is more potent mg for mg ??
I believe that Paxil has the highest affinity for the 5-HT transporter, while Celexa and Lexapro have been deemed the most selective. I don't know, but maybe Lexapro is more selective than Celexa.
Potency when used in this context refers to pharmacological properties, and not necessarily clinical efficacy. As Panda points out, Zoloft is often considered to be the more effective antidepressant, yet it is the least potent at binding to the 5-HT transporter.
- Scott
poster:SLS
thread:343730
URL: http://www.dr-bob.org/babble/20040505/msgs/344340.html