Posted by chemist on May 1, 2004, at 2:21:43
In reply to Re: please be civil » chemist, posted by TanyaJean on May 1, 2004, at 2:10:54
> "don't bad-mouth it on this board as the goal is to provide general information, not personal horror stories which in all likelihood will not be relevant to all genders, races, ages, and folks with other illnesses."
>
> OK, last post for me for a while. We're here because a forum was provided for us. I'm thankful for the "horror stories" because they do indeed give us much needed information, as do the "Non Horror Stories".
>
> This may not seem relevent, but bear with me. I saw a story on the news that people who take heart medication be wary of drinking grapefruit juice WITH the heart medication as it could cause serious problems, even death. Of course not EVERYONE who drank grapefruit juice with heart medication would suffer consquences, but it was on the news all the same. Why do people have such a problem with EFFEXOR and anti depressant side effects being so well publicized?
>
> It seems on this forum for people to talk about this very thing, the people sharing their stories are being talked down to. In many ways they're being told not to share what's happening. I may not be a chemist or doctor, but I know full well that what will happen to one person will not happen to everyone.
understood. the grapefruit thing is mainly limited to benzodiazepenes. a substance called bergamottin will decrease elimination of benzos via the CYP450 enzyme. it is both an inhibitor and inducer of CYP450. to the best of my knowledge, the bergamottin increase is most deleterious with bezos, but i stand corrected if you have peer-reviewed pubs indicating that heart medications - and there are numerous ones, as you know - interact with bergamottin and the CYP450 enzyme....all the best, chemist
poster:chemist
thread:1016
URL: http://www.dr-bob.org/babble/20040429/msgs/342085.html