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Re: Clarification on what neurotoxicity means » chemist

Posted by utopizen on April 28, 2004, at 15:40:40

In reply to Re: Clarification on what neurotoxicity means » utopizen, posted by chemist on April 27, 2004, at 22:41:32

. as for neurotoxicity: this is a well-established field, and the crux of the matter is that there are chemicals that can lead to pre-mature cell death (as opposed to apotosis).

by "well-established field," I assume you're referring to neurology. Neurology is a well-established field? Is this what is to be inferred? Please correct me if I am over-assuming here, but we're talking about a field of doctors that pat themselves on the back if they can diagnose a patient... I would consider a "well-developed" field to go beyond giving a patient a diagnosis and providing them with medicore care if at all underdeveloped.

And if it's so well-developed, why would we stil rely on neurotoxins? A developed field of toxicology, if that's what you're instead referred to, would exist only if it actually achieved something.

Like, say, helping researhcers not make drugs neurotoxic when they develop them by exploring how to prevent a drug's mechanism of action from causing neurotoxicity.

>>
the drugs being discussed inthis forum are more in-line with those that condition certain receptors for enhanced/inhibited uptake of certain neurotransmitters, and the receptors themselves are an entirely different matter....all the best, chemist
>>

condition? that suggests remission to me, IMHO. Few drugs offer remission to even fewer patients. And amphetamines certainly are discussed on this board a lot, and they are far from achieving the state of conditioning--

after one month of a drug holiday from Adderall, I received the same euphoria for a few minutes I initially experienced when I first went on it routinely a year prior.

And a lot of this is psychosomatic. The distinguishing factors are impossible to separate-- the amphetamine can cause shortness of breath, this causes the patient to feel anxious, causing an greater shortness of breath, causing lower CO2 levels in the blood, causing less CO2 flowing through the brain, causing damage to the brain.

Whether or not cells regenerate, it is clear that anxiety/stress itself, drug-induced or not, will lower IQ (Am. Textbook of Psychophamacology) and reducing anxiety or depression will alleviate much of this, especially through quality sleep and proper nutrition necessary for cellular functions to properly occur in the body.

My point was that neurotoxicity, brain cell loss, and controversies surrounding this are irrelevant, because concern should focus on the reality that much of this is managable, as it is psychosomatic action that plays the most signifigant role in degenerative effects brought on by drugs.


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