Posted by SLS on April 15, 2004, at 22:33:33
In reply to Re: really ? » SLS, posted by Budgie on April 15, 2004, at 12:37:33
> So does treatment resistance with the same med occur only when one stops after continual, sustained use?
It happens. But so too does resistance to a drug develop without stopping it - "poop-out".
> This is actually another reason why I'm wondering about the low-dose, as-needed thing- so that huge amounts of the drug never build up in my system in the first place.
I wish I knew enough to be able to encourage you or discourage you. I don't. It's a pretty weighty issue, though. You are the one who knows best how you feel. If you respond predictably and reliably to antidepressants when they are administered episodically "as needed", perhaps that's what's best for you. I guess it depends on how long is the interval between depressive episodes. But it does sound kind of funny for someone to say that they use antidepressants only when they need it as they get depressed every few days. Duh.
> I'm guessing, though, that there haven't been many studies on this phenomenon in relation to pulsing.
That's the thing. Sometimes there is nothing else to work with but anecdotes and a clinician's personal experience.
poster:SLS
thread:336019
URL: http://www.dr-bob.org/babble/20040412/msgs/336769.html