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Re: To Scott - memantine.... » SLS

Posted by Emme on April 13, 2004, at 12:21:13

In reply to Re: To Scott - memantine...., posted by SLS on April 13, 2004, at 8:03:42

Hi Scott,

> Based on my experience with memantine so far, I would say that it is worth pursuing.

I'll keep at it a bit. I don't think I've been at it long enough at a high enough dosage to be a fair trial yet.

> What is it about your condition that indicates bipolarity?

Ready? Here goes. :)

My pdoc feels there are several subtle signs that, taken together, point to some bipolar component. Profound anxiety and lots of sleep problems. Multiple poop-outs and inconsistent responses on ADs. I've had the best relief from ADs, but they seem to go south on me.

I've had mood cycling that doesn't actually involve going hypomanic per se. My therapist and I realized I seem to have two modes. In one mode I'm very sluggish, profoundly depressed. In the other mode, I'm keyed up, anxious, stressed, hypersentitive to noise, but still depressed. In my more agitated states, I've left orange smears on the office carpet by hurling carrots out into the hall.

My thoughts don't normally "race", though I have often been driven to distraction by worried, negative thoughts swooshing around in my head.

I did have a wee hypomanic time for about four days that had something to do with a mall.... There have been a few other times when I felt like the world was going too slowly. If I think the traffic where I live is too slow, then something's wrong. I've nipped it in the bud with a dash of seroquel. Several weeks ago I think I was flat out manic for an evening, with some wicked agitation in the days before and after. Hard to say how much of it was due to med changes....

So anyway, I'm nowhere near BP1, and don't have as pronounced hypomanic features as many BP2 people, but my depression isn't entirely straightforward either.

> I hope things turn around for you soon. It is hard to be patient with these lengthy drug trials when you are feeling so miserable. <grimace>

Agreed. sigh.

> Did I mention in one of my previous posts that the NIMH is conducting a trial of memantine for depression?

Thanks. I'll be interested to see how the it turns out...

Whoa. Thunder.. Gotta split and unplug my computer.

Keep haning in there!

Emme

 

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