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Re: lamictal come down ! » SLS

Posted by Peter S. on April 10, 2004, at 14:50:03

In reply to Re: lamictal come down !, posted by SLS on April 10, 2004, at 9:47:31

Scott:

Have you noticed any reduced efficacy over time on the LAM? How long have you been taking it? I'm currently on 50mg in the AM. I've tried taking another dose later but find that it doesn't work that well

Thanks!

Pete

> > > If I recall, the half-life of Lamictal is 11 hours.
>
> > Hmm, thats interesting. The monograph I was looking at said its half life is 30 hours and decreases for 20% after chronic administration. But I also could read somewhere else it varies from 10-40 hours.
>
> You are right. So much for the reliability of my recollection!
>
> Still, I do notice a definite loss of antidepressant effect if I miss a dose or two. I feel a boost almost immediately after dosing. I would give 100mg three times a day or perhaps 150 twice a day a try.
>
>
> - Scott


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poster:Peter S. thread:334331
URL: http://www.dr-bob.org/babble/20040407/msgs/334936.html