Posted by Sad Panda on April 10, 2004, at 1:39:53
In reply to MAOI + TCA- info please now!, posted by ace on April 10, 2004, at 0:24:49
> OK kids,
>
> Im going to try this stragedy after 1 more week of my tryptophan plan!
>
> Im in a rush and am a lazy bum so please answer these qstns which i am too lazy to look up!
>
> 1. How long would Nardil have to be stopped before adding the TCA
>
> 2. Could the TCA be Amitrypt???
>
> 3. Nardil + Reboxetine produced depression. Which TCA is least noradrenergic? (You get my gist?!)
>
>
>
> Peace and Happy Easter to all of you and Dr Bob!,
>
> Ace
> Nardil 60
> L-Tryptophan 2 gram
> Zyprexa 2.5
>
Hi Ace!> 1. How long would Nardil have to be stopped before adding the TCA
You should be able to add a TCA cautiously without stopping Nardil.
> 2. Could the TCA be Amitrypt???
NO! It is too Serotoninergic, even worse is Imipramine and Clomipramine.
> 3. Nardil + Reboxetine produced depression. Which TCA is least noradrenergic? (You get my gist?!)
Trimipramine.
The only reasons to add TCA's is for their NE activity to boost energy or as a low dose for sleep aids(Trimipramine or Doxepin). Best to add would be Desipramine or Nortriptyline. The Tertiary TCA all metabolize into NE boosting Secondary TCA's anyhow. Just because you had a bad reaction to Reboxetine doesn't mean you will have a bad reaction to the NE from TCA's.
Exactly what effect are you trying to achieve?
Cheers,
Panda.
poster:Sad Panda
thread:334782
URL: http://www.dr-bob.org/babble/20040407/msgs/334798.html