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Re: Need Help! Alot of Meds Nothing Helps Depress/Slee » PsychoSage

Posted by chemist on April 9, 2004, at 1:27:48

In reply to Re: Need Help! Alot of Meds Nothing Helps Depress/Slee, posted by PsychoSage on April 7, 2004, at 23:36:10

hi there....ephedra is bad news, wellbutrin has litle effect of serotonin, norepinephrine, and dopamine reuptake, and provigil is pretty light-weight. reboxetine most likely raised the ire of your doctor in that you are illegally bringing it into the US (i am assuming you are a US citizen, pardon me if you are in europe). strattera will do the job of keeping your synapses flooded with a moderate amount of norepinephrine, but it is not scheduled and is in fact a reformulation by lilly of a failed anti-depressant. trust me, i am in the pharmaceutical biz. caffeine is wonderful, but the real stimulants you are getting are theophylline and theobromine, which are _way_ more potent than caffeine, which itself has a long half-life for elimination (>12 hours) so you are not doing your self any favors by hitting the java all day. the other posters to your query are on target: you are over-medicated, and, most importantly, incorrectly medicated. i think any schizoaffective disorder is unlikely, and the problem with sluggishness is a result of the less-than-effective wellbutrin coupled with the questionable efficacy of straterra and concommitant ups and downs with ephedra and caffeine. in my opinion, a stronger morning dose than provigil is called for, perhaps ritalin or adderall; with adderall, the targets are very well defined and the elimination is 12 hours (half-life). if te depression persists, look into the next generation of mutli-targeted SSRIs, such as effexor, serzone, or lexapro (the S-enantiomer of the drug Celexa, with fewer side effects but anecdotal evidence suggest activation if taken late in the day). all the best, chemist


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