Posted by scott-d-o on April 5, 2004, at 12:07:19
In reply to effexor and ectasy, posted by artist on April 5, 2004, at 8:53:57
> thanks loads for all the replys. some of you seem very informed. it seems the ectasy and effexor won't mix.just out of intrest what does seratonin poisening do? is it fatal?
no need to worry about serotonin syndrome from this combination. ecstasy (3,4-methylenedioxyamphetamine) releases serotonin via reversing the action of the serotonin transporter (SERT), causing it to release serotonin into the synapse instead of taking it up into the cell like it normally does. effexor would almost entirely block any serotonin release induced by mdma, via it's occupation of the SERT. however, the supposed neurotoxicity of mdma is believed to be caused by excess dopamine at serotonin terminals. this seems to be a bunch of b/s thou and doesn't occur when the compound is used at common "recreational" doses.
poster:scott-d-o
thread:332813
URL: http://www.dr-bob.org/babble/20040402/msgs/332872.html