Posted by rod on April 1, 2004, at 4:17:02
In reply to The TD myth, posted by AMD on March 31, 2004, at 19:21:02
> Every other message discussing AP's on this board gives advice not to take these drugs except in 'extreme' cases of mania, etc., for fear of the dreaded TD. It's quite offensive, actually, to see these words thrown around, often perhaps discouraging a patient from using these classes of drugs where they might be very beneficial.
>
> My request is: put up or shut up. Next time someone warns about 'scary' TD, back it up with some facts: either your having had it, or a study showing it's a significant possibility given the drug in question. And by significant, I mean more than 1 in a 1000. I mean /death/ is a possible side effect of almost every drug, yet you never hear people running around saying, "don't take AD's, you might die!" Statistically speaking, it seems that TD occurs only rarely, and of these cases, only after long-term use (with the occasional exception). Particularly with newer AP's.Could you be so kind and provide some data to confirm that?
> If anyone has counter examples, feel free to cite them. I am not biased either way at this point, but it seems to me that there is some fearmongering present on this board.
>
> Thanks,
>
>
>I actually disagree. TD can be life devastating.
"Lower risk for tardive dyskinesia associated with second-generation antipsychotics: a systematic review of 1-year studies."
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14992963"... The weighted mean annual incidence of tardive dyskinesia for second-generation antipsychotics was 0% in the children, 0.8% (range=0.0%-1.5%) in the adults, 6.8% in the mixed adult and elderly population, and 5.3% (range=0.0%-13.4%) in the patients age 54 years and older, compared to 5.4% (range=4.1%-7.4%) in adults treated with haloperidol...."
I mean 6.8 % is more than 1/1000....
Roland
poster:rod
thread:330999
URL: http://www.dr-bob.org/babble/20040329/msgs/331172.html