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Re: New to Parnate - with a few questions

Posted by djmmm on March 18, 2004, at 19:20:50

In reply to New to Parnate - with a few questions, posted by Mr. Scott on March 18, 2004, at 17:45:19

> I am excited about beginning a trial of Parnate for my mixed anxious and depressed state that seems to encompass all the anxiety disorders and depressive disorders at the same time.
>
> I know I probably should have started with Nardil, but I tried that years ago and well I obviously didn't stay on it although it's hard to remember why exxactly. I have a hard time tolerating all meds but a particularly bad time with Wellbutrin and more recently the SSRI's.
>
> Is it normal to feel increasd anxiety (mild) and related symptoms on start-up? I will likely add in a benzo to calm that down. I'm only taking 20mg per day.
>
> Any input on what to expect and so on is much appreciated.

At 20mg, you should expect mild stimulation and motivation with a slight decrease in anxiety (phobic anxiety). You will probably have to increase to 30-40mg a day divided in 2 doses, taking the second dose no later than 2 in the afternoon (to help avoid insomnia---which for most is inevitable) At the higher dose you can generally expect a rapid increase in motivation, and rapid decrease in depression-- at least for me, the depression lifted almost immediately...it took a few weeks for my social phobia to improve.

FWIW, I think Nardil is a superior med for mixed depression/anxiety/phobic anxiety


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