Posted by King Vultan on March 8, 2004, at 8:06:09
In reply to Re: zoloft and dopamine, posted by Dave1 on March 7, 2004, at 17:49:34
> Hi,
>
> I get hand tremor, and my tongue sticks out involuntarily sometimes. This started since I hbegan taking Prozac, 3 months ago, for OCD.
> I am currently on 80mg/day.
>
>
> My question: What does all this Prozac/Dopamine relation data suggest about the possibility of developing a tardive dyskinesia like disorder if I continue on the Prozac long-term.
>
> Any input welcome.
>
> DaveTardive dyskinesia is caused by chronic blockade of dopamine receptors, as antipsychotic drugs do. This is the exact opposite of what is being discussed here, which is blockading dopamine reuptake, resulting in increasing dopamine transmission and consequent stimulation of those dopamine receptors. Your hand tremor is likely the result of stimulating serotonin 2A receptors from Prozac's blockade of serotonin reuptake.
Todd
poster:King Vultan
thread:321161
URL: http://www.dr-bob.org/babble/20040308/msgs/321969.html