Posted by scott-d-o on March 4, 2004, at 10:24:12
In reply to Re: Lexapro vs. Zoloft (sexual side effects), posted by SPhobia on March 3, 2004, at 19:31:28
> Zoloft: I'm up to 100mgs/day at this poing and have been titrating up on it for about 3 weeks. I may have a "slight" decrease in libido, but its so slight I am beginning to think it's my imagination (or due to increased stress in my work life). I am having NO PROBLEMS WITH ORGASMING!! This is the big one for me...I can't understand why Z has been SO different in this area for me than Paxil and Lexapro were. But who cares, I couldn't be happier about it. Also, I do NOT seem to be having the concentration problem I had on paxil.
>this is not suprising, since zoloft has a higher selectivity ratio for the da transporter vs. 5-ht transporter (ic50[5-ht] / ic50[da]) than any of the other ssri meds. generally, more da = less sexual se's, same goes for attention problems.
scott
poster:scott-d-o
thread:319709
URL: http://www.dr-bob.org/babble/20040304/msgs/320108.html