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Re: Buspar alone work for GAD for anyone?SSRI

Posted by micro on February 20, 2004, at 0:40:57

In reply to Re: Buspar alone work for GAD for anyone?SSRI, posted by Tony P on February 19, 2004, at 3:29:02

> In my experience, Buspar doesn't help that much with GAD, but people's response to it seems to vary greatly. By itself, the first time I tried it, it made me uncomfortably aggressive (my driving got really bad ;-), but then I was also withdrawing from benzos. The manufacturer of Buspar recommends NOT overlapping those two, precisely BECAUSE the Buspar doesn't have the GABA-mediated GAD relief/muscle relaxant effect that people are used to from benzodiazepines, so they naturally assume it isn't working.
>
> Having said that, I got really GOOD results for several years with Serzone plus Buspar - Serzone coped with my endogenous depression, had a slight anxiolytic effect and really improved my sleep; Buspar stopped my stress/rage/depression vicious cycle as well as boosting the antidepressant effect. I've used it successfully at 20-30mg/day with _very_ low doses of Serzone (100-200 mg/day). My guess is it would help with the stress/rage response by itself for _some_ people. YMMV, as usual.
>
> Tony P

Tony, I think your assessment has been validated many times in the literature. Buspar may be useful for augmentation, as monotherapy, it is a failure. One reason may be the fact that very anxious people are not patient people. [if at all] which is a real negative for individuals with high anxiety.

I am happy you are doing well. Micro
P.S. Some pcp's tell their patients that Buspar helps with Benzo withdrawl. Is anyone else hearing this?


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