Posted by sailor on February 17, 2004, at 12:45:46
In reply to Re: NEWS ON THE SELEGILINE PATCH!!!!!!!!!!!!!!!!!!!!!!, posted by lepus on February 16, 2004, at 22:13:03
Re: Patch Anticipation. After re-reading press releases, and a statement from Somerset's president (Somerset is the contracted producer for the patch), I'm still unclear about "final approval" and availability to the public. Dr. Sharoky (Pres. of Somerset) says: "we will work dilligently with the FDA on the specific additional requirements needed to obtain approval....) Feb. 2, 2004
For the poster asking about what the patch is for, it will be marketed primarily as a first line treatment for major depression. My guess is it will also be touted as appropriate for treatment resistant depression as well. This is a huge market, badly in need of new and more effective drug treatments. If the patch meets many peoples' expectations, this could be a big seller, with all the media hoopla that eventually follows. By the way, selegeline (l-deprenyl), is an MAOB inhibitor, which increases impulse propogation of dopamine and noradrenaline. Because of the transdermal delivery system, at low doses it does not cause the "cheese effect" which is a major drawback to oral forms of the drug. Undoubtedly, if found successful by patients and practitioners, it will be tried for numerous "off label" conditions as well, including the usual combination, augmentation addition of other psychotropics. I have a high personal stake in this new opportunity--I'm 57, and have suffered major depression for over 30 years, with varying success from drugs. It appears that my condition is worsening and getting more difficult to treat (a scary thought!). Right now I'm on 80mg/day Parnate with modest benefit. Bring on the patch!! Patience, Persistence. Regards, Sailor
poster:sailor
thread:314102
URL: http://www.dr-bob.org/babble/20040215/msgs/314670.html