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Tricyclic antidepressants queries

Posted by irwind on February 12, 2004, at 17:25:37

i am a little confused about some of the stuff i read about tricyclic antidepressants (TCA's).
i am particualrly confused about their (TCA's)
action on noradrenaline/norepinephrine.
i have read that they (TCA's) work by increasing their amounts in the brain. but i also read as a
side effect alpha-adrenolytic action it causes vasodilation and may cause hypotension.
the two actions are exactly the opposite of each other.
please it would be great if some one clarifies this for me.
irwind


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poster:irwind thread:312558
URL: http://www.dr-bob.org/babble/20040210/msgs/312558.html