Posted by Chairman_MAO on February 10, 2004, at 20:07:45
In reply to strattera vs. selegilene for ADD, posted by zeugma on February 10, 2004, at 17:45:48
>but I wonder if there isn't something better out there, and this selegilene patch is the only plausible possibility. How does selegilene compare to Strattera as an ADD med?
Selegiline has myriad mechanisms of action (I mean, one could easily write 4 pages _summarizing_ everything it does) in addition to MAO inhibition; I wouldn't be surprised if in the higher doses the patch allows for it would be a robust ADD med. My guess is that the patch would be better for inattentive ADD/adult AD[H]D whereas Strattera is better as a chemical straightjacket for children in classrooms. Or, to phrase it differently, I found selegiline to be a mood-brightening cognitive enhancer that increased my "joi de vivre" whereas atomoxetine dampened my emotions and allowed me to "zone in" more easily without feeling distracted. Atomoxetine is good for melancholic depression, probably, but I doubt it provides the coarse effect that 20-40mg/day of selegiline does.
>what about its antidepressant properties?
see above
>Does selgilene help with social anxiety as well?
It probably helps with the motivational "oh-I-think-I'll-talk-to-those-people" and cognitive "I-feel-like-I-know-what-to-say-and-enjoy-saying-it" aspects of social PHOBIA. Insofar as the actual "I-feel-physically-anxious-and-it-makes-me-uncomfortable" is concerned, that probably depends upon the individual and/or requires 30mg/day or more of selegiline (so you get some serotonergic effect). But who knows, this is wild conjecture on my part.
>Does it cause problems with insomnia?
Unless amphetamine puts you to sleep, it will.
poster:Chairman_MAO
thread:311818
URL: http://www.dr-bob.org/babble/20040210/msgs/311859.html