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Re: Chairman-do you have links to amphet for ocd » BobS.

Posted by Chairman_MAO on February 9, 2004, at 20:06:29

In reply to Chairman-do you have links to amphet for ocd, posted by BobS. on February 9, 2004, at 17:50:29

If I were enrolled in school now I'd try to get you the text. Basically, this is my theory:

If you have a properly dosed buzz (e.g., not too much, not too little, and 30mg is a proper dose of d-amphetamine), you are less likely to be obsessive. ;)

Ritalin's a crappy buzz.

Woolley JB, Heyman I.
Related Articles,Links

Dexamphetamine for obsessive-compulsive disorder.
Am J Psychiatry. 2003 Jan;160(1):183.

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J Clin Psychopharmacol. 1991 Aug;11(4):237-41.

Acute psychostimulant challenge in primary obsessive-compulsive disorder.

Joffe RT, Swinson RP, Levitt AJ.

Department of Psychiatry, Toronto General Hospital, Ontario, Canada.

The effects of acute oral administration of methylphenidate 40 mg versus dextroamphetamine 30 mg versus matched placebo were compared in 11 patients with primary obsessive-compulsive disorder. Dextroamphetamine but not methylphenidate had a significantly greater antiobsessive-compulsive effect as measured by the Comprehensive Psychiatric Rating Scale--Obsessive-Compulsive Subscale, as compared with placebo. This effect appeared unrelated to their effect on depression although a differential effect of the two psychostimulants on anxiety was observed. Although both these stimulants affect serotonin, the differences noted between dextroamphetamine and methylphenidate suggest that catecholamines may be implicated in the pathophysiology of obsessive-compulsive disorder.


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