Posted by Doctor Feel Good on January 28, 2004, at 23:47:49
In reply to Re: Seroquel - Ambien, posted by EscherDementian on January 28, 2004, at 23:14:09
That's awful. If Ambien did that to you, then your problems may stem from GABA anomalies. Perhaps you could look into Gabitril. It is prescribed for epilepsy, but I know of a couple friends who had it prescribed for anxiety, and they are doing quite well. Their anxiety was severe (they thought they were panic attacks). Good luck buddy! P.S. Are you currently on other meds, and have u had a physical including a thyroid test?
GABITRIL—A Selective GABA Reuptake Inhibitor (SGRI)
Increases GABA levels in vitro by selectively binding to GAT-1, the predominant GABA uptake transporter
Proven safety profile with a low potential for drug interactions
Linear pharmacokinetics offer predictable systemic exposure
More than 14 million patient days of exposure to GABITRIL therapy
The precise mechanism by which GABITRIL exerts its effect in humans is unknown
GABITRIL is indicated as adjunctive therapy in adults and children 12 years and older in the treatment of partial seizures.This except is taken from Gabitril.com, these are their references.
References:
1. Borden LA, Murali Dhar TG, Smith KE, Weinshank RL, Branchek TA, Gluchowski C. Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1. Eur J Pharmacol. 1994;269:219-224.
2. GABITRIL package insert, Cephalon, Inc.
3. Data on file, Cephalon, Inc.
4. Giardina WJ. Anticonvulsant action of tiagabine, a new GABA-uptake inhibitor. J Epilepsy. 1994;7:161-166.
5. Schachter SC. Tiagabine: current status and potential clinical applications. Exp Opin Invest Drugs. 1996;5:1377-1387.
6. Fink-Jensen A, Suzdak PD, Swedberg MDB, Judge ME, Hansen L, Nielsen PG. The g-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats. Eur J Pharmacol. 1992;220:197-201.
poster:Doctor Feel Good
thread:302023
URL: http://www.dr-bob.org/babble/20040127/msgs/306747.html