Posted by SandyWeb on January 28, 2004, at 12:52:34
In reply to Re: Neurontin--new user, posted by thinkfast on January 28, 2004, at 6:36:36
Chemical Effect: Unknown; although structurally related to gamma-amino butyric acid (GABA), drug doesn't interact with GABA receptors and converted metabolically into GABA or a GABA agonist.
Absorption: bioavailability isn't dose proportional but averages about 60%
Distribution: drug circulates largely unbound to plasma protein
Metabolism: not appreciably metabolized
Excretion: excreted by kidneys as unchanged drug
Half-life: 5-7 hours
Pharmacologic class: 1-aminomethyl cyclohexoeacetic acid
poster:SandyWeb
thread:301797
URL: http://www.dr-bob.org/babble/20040127/msgs/306467.html