Posted by Sad Panda on January 25, 2004, at 23:25:22
In reply to would any Dr prescribe the effex.rem mix?, posted by Rainee on January 25, 2004, at 7:13:16
> Major Interaction -- Drug-Drug
> venlafaxine and mirtazapine
>
> MONITOR CLOSELY: The combining of agents that can inhibit serotonin reuptake and/or other agents with serotonergic activity (including some medications for migraine therapy and certain opioids) may potentiate the risk of serotonin syndrome, which is a rare but serious and potentially fatal condition thought to result from hyperstimulation of brainstem 5-HT1A receptors. MANAGEMENT: In general, the concomitant use of multiple serotonergic agents should be avoided if possible, or otherwise approached with caution if potential benefit is deemed to outweigh the risk. Close monitoring is recommended for signs and symptoms of excessive serotonergic activity such as CNS irritability, altered consciousness, confusion, myoclonus, ataxia, abdominal cramping, hyperpyrexia, shivering, pupillary dilation, diaphoresis, hypertension, and tachycardia. Particular caution is advised when increasing the dosages of these agents.
>
>
> This scared me but what you said felt hopeful to get me up and moving...RaineeThanks for the heads up :) I think the risk of serotonin syndrome with Remeron+Anything is largely theoretical. I like Remeron because it reverses all the SSRI side effects caused by Efexor + it gives the best sleep I've had in my whole life.
Cheers,
Panda.
poster:Sad Panda
thread:305256
URL: http://www.dr-bob.org/babble/20040122/msgs/305470.html